History

ေဆးတကၠသိုလ္၊ေတာင္ႀကီးဖြဲ႕စည္းတည္ေထာင္ဖြင့္လွစ္ျခင္းႏွင့္အတူဇီဝဓါတုေဗဒဌာနဖဲြ႕စည္းတည္ေထာင္ခဲ့ပါသည္။

Department Of Biochemistry (Former Heads)

Former Head

ဇီဝဓါတုေဗဒဌာန၏ ပထမဦးဆံုးပါေမာကၡ/ဌာနမွဴးမွာပါေမာကၡေဒါက္တာလွလွရီျဖစ္ပါသည္။ ပါေမာကၡေဒါက္တာလွလွရီသည္ ေဆးတကၠသုိလ္(၁)ရန္ကုန္၊ ဇီဝဓါတုေဗဒဌာန၊ တြဲဖက္ပါေမာကၡ ရာထူးမွ ေဆးတကၠသိုလ္(ေတာင္ႀကီး) ဇီဝဓါတုေဗဒဌာနပါေမာကၡ/ဌာနမွဴး ရာထူးသို႕ တိုးျမႇင့္ခန္႕ထားျခင္းခံရၿပီး ၂၀၁၆ခုႏွစ္၊ ေဖေဖာ္ဝါရီလ (၁၁)ရက္ေန႕မွစ၍ ယေန႕အထိပါေမာကၡ/ဌာနမွဴး လုပ္ငန္းတာဝန္မ်ားကိုထမ္းေဆာင္ခဲ့ပါသည္။

Dr Hla Hla Yee

Name : Prof: Dr. Hla Hla Yee
Rank : Professor / Head
Degree : M.B.B.S , M.Med.Sc (Biochemistry)
Phone : 09-799899110
E-mail address :  hla2yee2015@gmail.com

Department Of Biochemistry (Academic Staffs)

bio1

Name : Dr. Aye Khine Khine Win
Rank : Associate Professor
Degree : M.B.,B.S., M.Med.Sc (Biochemistry)
Phone : 09-5030677
E-mail address :  akkwmoe92@gmail.com

Name : Dr. Ei Ei Phyo Myint
Rank : Assistant Lecturer
Degree : M.B.,B.S, M.Med.Sc (Biochemistry)
Phone : 09-977481998
E-mail address : dreepm85@gmail.com

Name : Dr. Htet Akar
Rank : Demonstrator
Degree : M.B.,B.S
Phone : 09-421070403
E-mail address : htetloonnyo@gmail.com

Name : Dr. Aye Nyein Mon
Rank : Demonstrator
Degree : M.B.,B.S
Phone : 09-254174289
E-mail address : Ayenyeinmon@gmail.com

Name : Dr. Nway Thaw Dar Aung
Rank : Demonstrator
Degree : M.B.,B.S
Phone : 09-421087193
E-mail address : dr.ntda@gmail.com

Name : Dr. Htet Htet Aung
Rank : Demonstrator
Degree : M.B.,B.S
Phone : 09-795601975
E-mail address : bugsbunng1345@gmail.com

Name : Dr. Eaint Thel Thel Oo
Rank : Demonstrator
Degree : M.B.,B.S
Phone : 09-73242377
E-mail address : eaintthel@gmail.com

bio2

Name : Daw Khin Moe
Rank : Lab boy -5
Degree :
Phone : 09-795375875
E-mail address :  khinmoetun1821989@ gmail.com

Name : Daw Hnin Marlar Nwe
Rank : Peon
Degree :  B.A (Geo:)
Phone : 09-797188825
E-mail address : rlove9979@gmail.com

Name : U Nway Aung Zaw
Rank : Cleaner
Degree :  B.A (Geo:)
Phone : 09-794127176
E-mail address :

2015-2016 Academic Year

Courses

  1. Teaching hours

Teaching hours available for 2nd  MBBS Course :

Total                           =   665 hours

  1. Breakdown of teaching hours:

Lectures                                                                     =   295

Tutorials                                                                    =   195            607 hours

Practicals                                                                   =   117

  1. Class tests (4 in number) + Practical Test:

Theory (MCQ & MSQ), Practical                   58    hours

Grand Total                          665  hours

TEACHING   COURSE

 

1 INTRODUCTION TO BIOCHEMISTRY

Basic Principal and importance of

Biochemistry in relation to other sciences

2 CHEMICAL BASIS OF LIFE
          Chemical composition and organization of a cell
          Carbonhydrate
          Lipids
         Amino acids and Proteins
         Nucleic acids DNA, RNA
         Chemical composition and organization of membranes

3 ENZYMOLOGY
         Definition, chemical structure and properties of  enzyme   enzyme
         Distribution of enzyme
         Classification of enzyme
         Coenzymes, cofactors and abzymes and their functions
         Isoenzyme and its biomedical importance
         Mechanism of enzyme action
         Factors affecting the velocity of enzyme catalyzed reactoin
         Enzyme inhibition
         Biomedical importance of enzyme inhibition
         Regulation of enzyme activity
         Medical aspect of enzymology

4. BIOENERGETICS & BIOLOGIC OXIDATION
         Laws of thermodynamics
         Extraction of chemical energy by a cell
         Mitochondria and energy extraction
         Respiratory chain, Oxidative phosphorylation
         Biomedical importance of inhibitors and uncouplers
         Energy rich compounds and their functions
         Biologic oxidation
         Enzymes and coenzyme involved in biologic oxidation
         Reactive oxygen species and oxidative stress of the cell
5. ENERGY METABOLISM
Sources and utilization of energy
Energy balance and it’s regulation
Metabolic rate(MR) and Basal metabolic rate(BMR)
Factors affecting MR and BMR
Application of BMR in clinical medicine
Obesity
6.  BIOCHEMISTRY OF HORMONES
Cell signaling
Signaling mechanism of special senses
Signaling mechanisms of growth factors and cytokines
Second messengers
General characteristics of hormones
Biosynthesis and signaling mechanisms of hormones
Hormone involved in calcium metabolism
       Importance of cell signaling in diseases and it’s clinical application
7. MOLECULAR BIOLOGY
Organization of genomes and chromosomes of Prokaryotes & Eukaryote
Central Dogma of molecular biology
Functional genes
Genetic code and its importance
Biomedical aspect of genomic stability and Mutation
Genetic diseases
Gene expression
Regulation of gene expression
Cell cycle and apoptosis
DNA replication, reverse transcription
DNA damage and repair
Oncogenes and tumour biomakers
Recombinant DNA technology, cloning, PCR
Human genome project, Gene therapy and stem cell therapy
8. CHEMISTRY OF BLOOD
Components and functions of blood
Haemoglobin structure, functions
Normal and abnormal variants of Heamoglobin
Synthesis and breakdown of Hb and their biomedical importance
Plasma proteins and their functions
Factors maintaining plasma protein level
Biochemistry of Proteins that involves in immune system (Immunoglobulins, Complement proteins, cytokines)
Biochemical mechanism of blood coagulation and anti-clotting and their importance

 

9. CHEMISTRY OF RESPIRATION
Gas laws and biochemical aspect of respiration
General process of gas transfer
Transport of respiratory gases O2 and CO2
Molecular mechanism of O2 binding to Hb
Oxygen haemoglobin dissociation curve and it’s significance
Factors influencing O2 dissociation.
 ( pH, Temp, electrolytes, CO, CO2 & 2,3 BPG)
Carbon monoxide toxicity
Oxygen binding ability of Hb variants (HbF, HbS, Methaemoglobin etc.)
Myoglobin
Clinical applications of blood gases analysis

10 FOOD & NUTRITION
Energy aspect of diet
Nutritional importance of carbonhydrate, fat and protein
Dietary fibre
Nitrogen balance
Nutritional and biochemical aspect of fat soluble and water soluble vitamins
Energy releasing vitamin
Antioxidant vitamins
Haemopoietic vitamins
Anti-vitamins
Minerals
Composition of a balanced diet
Principle in planning of balanced diet
Nutritional and biochemical aspect of genetically modified foods
11 BIOCHEMISTRY OF DIGESTION & ABSORPTION
Digestion and absorption of carbonhydrate and it’s clinical importance
Digestion and absorption of proteins and it’s clinical importance
Digestion and absorption of lipids and it’s clinical importance
Digestion and absorption of nucleoprotein
Absorption of water and minerals
Absorption of vitamins
Absorption in large intestine
12 BIOCHEMISTRY OF LIVER AND BILIARY SYSTEM
Functions of liver
Liver function tests and its clinical uses
Bile : composition and fuctions
Synthesis and functions of bile salts
Biochemical mechanism of gall stone formation
Biomedical importance of liver and biliary system
13 ACID BASE BALANCE
Fundamental concepts of acid balance
Acid and base production in the body
Regulation of hydrogen ion concentration
Regulation by buffer mechanism
Respiratory adjustment
Renal adjustment
Acid base disturbances
Metabolic acidosis and alkalosis
Respiratory acidosis and alkalosis
Importance of anion gap in acid base imbalance
Assessment of acid base status
14 FLUID & ELECTROLYTES
  Body fluid compartment, distribution of water
  Factors affecting Total body water
  Importance of plasma electrolytes
  Principle of measurement of fluid compartment
  Functions of water and electrolytes
  Water balance (daily intake and output of water)
  Regulation of ECF volume and osmolarity
  Disturbances of sodium and water metabolism
   (dehydration, overhydration)
Fluid shif

15 CARBONHYDRATE METABOLISM
Overview of carbonhydrate metabolism
Fate of glucose, fate of G6P
Glycolysis and it’s biomedical importance
Fate of pyruvate, clinical aspects of pyruvate metabolism
HMS pathway and it’s biomedical importance
Uronic acid pathway and it’s significance
Glycogen metabolism
Gluconeogenesis, Citric acid cycle and their metabolic significance
Blood glucose regulation
Metabolism of fructose and galactose, and their metabolic significance
Glucose tolerance test
Glycated protein in diabetes and their significance
Importane of glycated haemoglobin (HbA1c), sorbitol pathway and oxidative stress in development of diabetic complications
16 LIPIDS METABOLISM
Overview of lipid metabolism
Metabolism of fatty acid
Metabolism of ketone bodies and it’s clinical significance
Metabolism of triacylglycerol and significance
Metabolism of adipose tissues and significance
Metabolism of ecosanoids and their significance
Metabolism of phospholipid and it’s significance
Metabolism of cholesterol, biosynthesis, regulation of biosynthesis
Blood cholestorol level and factors control
Lipid transport ; metabolism of lipoproteins and their significance
Importance of lipid peroxidation
Importance of abnormal lipoprotein metabolism in obesity, atherosclerosis and fatty liver
17 PROTEIN & AMINO ACID METABOLISM
  Overview of amino acid metabolism
  Biosynthesis of nutritionally non-essential amino acids
  Protein degradation
  Catabolic fate of amino acid
  Metabolism of ammonia and it’s significance
  Urea cycle, blood urea and it’s significance
  Anabolic fate of amino acids
  Conversion to specialized products and Neurotramsmitters
  Disorders of protein degradation and amino acid metabolism
  Amino acid pool
Specialized proteins of extracellular matrix, collagen, elastin etc.
18 NUCLEOPROTEIN METABOLISM
Biomedical importance of nucleotides
Synthesis of purine nucleotides metabolism
Catabolism of nucleic acid
Outline pathway of purine breakdown
Blood uric acid
Factors affecting blood uric acid level
Metabolism of pyrimidine, outline synthesis and breakdown
19 INTEGRATED METABOLISM
Common metabolic pool
Role of liver in metabolism
Metabolic changes during Fed state and Fast state
Metabolic disorders in Diabetes, atherosclerosis, obesity

Activities

ေတာင္ႀကီး MMA အသင္းႏွင့္အတူ Seminor မ်ား၊ lunch time talk မ်ား ပါ၀င္ေဆာင္ရြက္သည္။

Future Programme

Test  II                           – June 26-30 /2017

Test  III                          -Oct  16-27 /2017

Test IV                           -Jan  15-19 /2018

Practical                         -Feb 5-9/ 2018

 

PBL    I           (3.7.2017-7.7.2017)

PBL    II         (30.10.2017-3.11.2017)

PBL    III        (22.1.2018-26.1.2018)

 

Integrated curriculum will be started from 2018- 2019